Case study: hock lesions as a potential source of Staphylococcus aureus mastitis

Hock injuries are a common injury in dairy cows that are housed indoors for the greater part of the year. Oftentimes, the lesions indicate inadequate stall or cubicle design in dairy barns. The presence and severity of hock lesions are associated with lameness and other disorders of the limb, which is why most welfare evaluations target hock lesion reductions to improve cow welfare. It is thought that hock lesions may also be associated with mastitis and reduced milk yield. In order to better understand the association between hock lesions and the development of Staphylococcus aureus mastitis, an undergraduate student from the University of Vermont (UVM), US headed-up a case study within the student-run herd as a senior thesis project with the help of her advisor Dr. John Barlow and his graduate students. Veterinarian and UVM PhD student Caitlin Jeffrey presented the findings at the National Mastitis Council Annual Meeting, held in February of this year.

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Diego B. Nobrega working on antimicrobial use and resistance in Canadian dairy herds

Antimicrobial resistance (AMR) is one of the most important threats to human and animal health. There are indications of a pending “post-antibiotic era” where AMR will cause 10 million human deaths per year globally by 2050 if no serious action is taken (O’Neill, 2016).

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State-of-the-art mouse models as an innovative preclinical tool to study the current challenges in mammary gland inflammation

The past decade, the laboratory of Biochemistry, based at the Faculty of Veterinary Medicine (Ghent University, Belgium), has gained unique expertise in the development and validation of preclinical in vivo models to study mammary gland inflammation. Under the supervision of…...

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Mastitis Research Program Activities at the University of Minnesota

When I arrived at the University of Minnesota in 1998 as a newly minted assistant professor, I had then only just begun to dabble in mastitis research…. This content is for M²-DIGITAL, M²-PREMIUM, M²-PARTNERS & NMC members only.Login or  Join...

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Prof. Marcos Muñoz at work in his laboratory in Chile

Prof Marcos Muñoz is a veterinarian at the Universidad de Concepción, in Chile.

He collaborates in mastitis research with different countries and he is the vice president of the Latin American Mastitis Research Network, RELIM…. This content is for M²-DIGITAL, M²-PREMIUM, M²-PARTNERS & NMC members only.Login or  Join Now and get instant Premium...

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Several assay models are used to evaluate novel therapeutic approaches. Here, bovine mammary gland epithelial cells are cultured and used to study the interactions of bacteria with host cells. Promising therapies are subsequently evaluated in a mouse mastitis model and ultimately by means of experimental infections in cows.

Novel control and treatment approaches for Staphylococcus aureus intramammary infections [Longread]

Bovine mastitis is an inflammation of the udder, which most often results from an intramammary infection (IMI)…. This content is for M²-DIGITAL, M²-PREMIUM, M²-PARTNERS & NMC members only.Login or  Join Now and get instant Premium access....

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Dissecting the early host response during pathogen-specific mastitis

The clinical picture of bovine mastitis is mostly related to the causative pathogen; however, the underlying reasons remain unclear. A deeper understanding of the pathogen-specific mechanisms leading to their divergent clinical pictures may be crucial in future for the development…...

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Dr. Anja Sipka collecting and evaluating milk samples at the dairy farm for milk leukocyte differentiation.

Understanding and preventing mastitis in dairy cows – Immune regulation in the mammary gland

The immune system of the dairy cow is a much-studied subject but despite growing effort a lot of key mechanisms regulating mastitis remain enigmatic…. This content is for M²-DIGITAL, M²-PREMIUM, M²-PARTNERS & NMC members only.Login or  Join Now and get...

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Improving mastitis detection in the laboratory and on the farm

New markers and assays from Porto Conte Ricerche, Sardinia – In addition to the well known problems in dairy cows, mastitis causes significant losses on small ruminant dairy farms. The impact on milk quantity and quality of the subclinical disease…...

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