Researcher@work

Researcher@work

The immunity-AMR Project: A new Op+lait initiative

A new multidisciplinary research team composed of Christopher Fernandez-Prada, David Langlais, Jocelyn Dubuc, Éric Paquet, and Simon Dufour, based in the province of Québec, and involving multiple centers (UdeM, McGill, and U. Laval), has decided to explore how genetic mutations may contribute to cases of antibiotic treatment failure, AMR, and persistent or recurring infections in dairy cows. If these mutations can be identified, the research team could develop new tests to predict how easily a cow will get sick. In addition, the research team will also shed new light on how a weak immune system can lead to an increased frequency of AMR infections in dairy cows.

Read More
Researcher@work

Case study: hock lesions as a potential source of Staphylococcus aureus mastitis

Hock injuries are a common injury in dairy cows that are housed indoors for the greater part of the year. Oftentimes, the lesions indicate inadequate stall or cubicle design in dairy barns. The presence and severity of hock lesions are associated with lameness and other disorders of the limb, which is why most welfare evaluations target hock lesion reductions to improve cow welfare. It is thought that hock lesions may also be associated with mastitis and reduced milk yield. In order to better understand the association between hock lesions and the development of Staphylococcus aureus mastitis, an undergraduate student from the University of Vermont (UVM), US headed-up a case study within the student-run herd as a senior thesis project with the help of her advisor Dr. John Barlow and his graduate students. Veterinarian and UVM PhD student Caitlin Jeffrey presented the findings at the National Mastitis Council Annual Meeting, held in February of this year.

Read More
Prof. Marcos Muñoz at work in his laboratory in Chile
NMCResearch | Free accessResearcher@work

Prof Marcos Muñoz is a veterinarian at the Universidad de Concepción, in Chile.

He collaborates in mastitis research with different countries and he is the vice president of the Latin American Mastitis Research Network, RELIM. This content is for M²-DIGITAL, M²-PREMIUM, M²-INSTITUTIONAL & NMC members only. Log in if you have a valid subscription and continue your reading Or Join us today (subscribe)Read more

Read More
Several assay models are used to evaluate novel therapeutic approaches. Here, bovine mammary gland epithelial cells are cultured and used to study the interactions of bacteria with host cells. Promising therapies are subsequently evaluated in a mouse mastitis model and ultimately by means of experimental infections in cows.
Researcher@work

Novel control and treatment approaches for Staphylococcus aureus intramammary infections [Longread]

Bovine mastitis is an inflammation of the udder, which most often results from an intramammary infection (IMI). This content is for M²-DIGITAL, M²-PREMIUM, M²-INSTITUTIONAL & NMC members only. Log in if you have a valid subscription and continue your reading Or Join us today (subscribe) and get instant premium accessRead more

Read More
Dr. Anja Sipka collecting and evaluating milk samples at the dairy farm for milk leukocyte differentiation.
Researcher@work

Understanding and preventing mastitis in dairy cows – Immune regulation in the mammary gland

The immune system of the dairy cow is a much-studied subject but despite growing effort a lot of key mechanisms regulating mastitis remain enigmatic. This content is for M²-DIGITAL, M²-PREMIUM, M²-INSTITUTIONAL & NMC members only. Log in if you have a valid subscription and continue your reading Or Join usRead more

Read More