The goal of this thesis was to investigate three main aspects of mastitis due to Streptococcus uberis; (i) the epidemiology of clinical bovine mastitis, including the relative importance of cow-to-cow transmission and acquisition from an environmental source as well as the occurrence of persistent infection and re-infection, (ii) factors affecting biofilm formation of S. uberis, and (iii) the virulence factors of S. uberis.
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